Abstract: As a living environment or biotope of the human species, urban structures must meet not only the economic, social and political rights of the people, but also their biological and neurophysiologic requirements. A new scientific approach to urban planning is biourbanism or organic urbanism, which considers the urban environment as being a hyper-complex living thing. From the scientific point of view, this approach opens the way to new scenarios for urban planning research. The aim of the study is to promote this modern concept of urban planning for Bucharest City in the context of its climate vulnerability. The objectives of our investigation are the following: analyzing the dynamic of climate conditions of the city, highlighting the weather risks for the population and devising scenarios for implementing the concept in Bucharest. The research methodology focused on the following: the discussion of conceptual framework based on specialty literature, the calculation of bioclimatic indices in order to assess the city’s vulnerability to climate conditions and the presentation of “biourban” improvement models applicable to urban fabric samples. The study reveals the vulnerability of Bucharest City in relation to the specific risks associated to the weather phenomena of the summer season (high temperatures and moisture deficit), as argument in favour of preparing implementation scenarios for biourbanism ideas.